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KMID : 1134819960250050865
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Journal of the Korean Society of Food Science and Nutrition
1996 Volume.25 No. 5 p.865 ~ p.870
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Antitumor Effect of Persimmon Leaves in vivo using Sarcoma - 180 Cells
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Moon Suk-Hee
Kim Kwang-Hyuk
Park Kun-Young
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Abstract
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Antitumor effects of hexane, chloroform fractions and tannins from persimmon leaves were studied by using sarcoma-180 tumor cells. The solid tumor growth was inhibited most effectively when 0.5㎎/㎏ of hexane fraction was administerated to the Balb/c mouse. The life prolongation effects were 35.6%, 11.5% and 29.9%, respectively when hexane fraction, chloroform fraction and tannins from the persimmon leaves were administerated to the mouse. Spleen index, a marker for immunological activity, was increased in mice administrated hexane fraction, chloroform fraction and tannins of persimmon leaves, compared with the control group.
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KEYWORD
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antitumor effects, persimmon leaves, sarcoma-180 tumor cells
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